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Nicotine Nasal Spray. Nicotine nasal Comparative randomised active drug controlled clinical trial of a herbal eye drop in computer vision syndrome. A comparative double-blind placebo-controlled clinical trial of a herbal eye drop itone was conducted to find out its efficacy and safety in patients with computer vision syndrome.
Patients using computers for more than 3 hours continuously per day having symptoms of watering, redness, asthenia, irritation, foreign body sensation and signs of conjunctival hyperaemia, corneal filaments and mucus were studied. One hundred and twenty patients were randomly given either placebo, tears substitute tears plus or itone in identical vials with specific code number and were instructed to put one drop four times daily for 6 weeks.
Subjective and objective assessments were done at bi-weekly intervals. In computer vision syndrome both subjective and objective improvements were noticed with itone drops.
Itone drop was found significantly better than placebo pcomputer vision syndrome. A decrease in nasal CO2 stimulates breathing in the tegu lizard. Tegu lizards decrease ventilatory frequency f when constant CO2, as low as 0. The purpose of the present study was to investigate further the effect of nasal CO2 pattern on f in tegu lizards. Ventilation was measured using a pneumotachograph and pressure transducer in-line with an endotracheal T-tube inserted through the glottis.
CO2 was delivered to the nasal cavities through small tubes inserted into the external nares. The failure to link the phasic CO2 ventilatory response to a phase in the respiratory cycle indicates that the nasal CO2 receptors do not participate in the breath-by-breath regulation of breathing in these lizards. The observation that small decreases in nasal CO2 abolished the f inhibition caused by constant nasal CO2 provides further evidence for the ability of the nasal CO2 receptors to distinguish between pulsed and constant CO2.
Escherichia coli were the most frequently 39 isolated followed by Citrobacter freundii 33, Klebsiella pneumonia 27, Salmonella indica 12, Enterobacter gergoviae 12, and Ent.
Other important bacteria isolated from gecko droppings were Listonella damsela 2, Raoultella terrigena 3, S. Of the isolates tested for antimicrobial drug sensitivity, 27 The most effective herbal drug, Ageratum conyzoides extract, inhibited growth of only Nasal Physiology. Nasal Anatomy.
Nasal packing with ventilated nasal packs; a comparison with traditional vaseline nasal pack. To compare the benefits of ventilated nasal packing with traditional vaseline guaze nasal packing. Study Design: Randomized controlled trial.
Patients were divided in two groups using lottery method endotracheal tube and piece of surgical glove filled with ribbon guaze was utilized for fabricated ventilated nasal pack and compared with traditional nasal packs. Nasal obstruction and sleep disturbance were studied at eight hours and twenty-four hours following surgery using visual analog scale.
Results: Mean nasal obstruction with ventilated nasal pack was Mean sleep disturbance in both the groups was Conclusion: Patients with ventilated nasal packs were found to have better tolerance to nasal packs due to less nasal obstruction and sleep disturbance. This article discusses the characteristics of cmmunity herbal monographs for traditional herbal medicinal products and its establishment procedure. It also reviews the new development of cmmunity traditional herbal monographs.
The purpose is to clarify the relationship between cmmunity herbal monographs and simplified registration for traditional herbal medicinal product in European Union and provide reference to the registration of taditional Chinese mdicinal products in Europe.
Comparing the effects of ketotifen fumarate eye drops and ketotifen oral pills on symptom severity and quality of life in patients with allergic rhinitis: a double-blind randomized clinical trial. Allergic rhinitis is a chronic inflammatory disease of nasal mucosa. Previous studies have shown the therapeutic effects of ketotifen eye drops on allergic conjunctivitis and rhinitis patients.
This study was designed to compare the effects of ketotifen drops and oral ketotifen pills on symptoms and quality of life in allergic rhinitis patients. In this double-blind randomized clinical trial, patients with mild allergic rhinitis who were referred to the allergy clinic of Baqiyatallah Hospital from March to April were randomly allocated to 2 groups; the first group received ketotifen drops 1 drop every 12 hours with placebo pills 2 pills daily , and the second group received placebo eye drops with ketotifen pills for 4 weeks.
Symptoms sneezing, runny nose, itching, and nasal obstruction severity were examined and Rhinitis Quality of Life Questionnaire RQLQ scores were evaluated in the second and fourth weeks. A total of patients were evaluated in 2 groups.
The mean age was Both groups showed a significant improvement in rhinorrhea, nasal congestion, nasal itching, coughing, sneezing, RQLQ, and nasal smear eosinophil percent compared to baseline amounts p drops group p drops in patients with allergic rhinitis and their easy availability in Iran, using this medication instead of systemic therapies is suggested. Nevertheless, more studies are required to evaluate the long-term effects of using this drug and the recurrence rate of symptoms.
Nasal deposition of ciclesonide nasal aerosol and mometasone aqueous nasal spray in allergic rhinitis patients. Sensory attributes of intranasal corticosteroids, such as rundown to the back of the throat, may influence patient treatment preferences. This study compares the nasal deposition and nasal retention of a radiolabeled solution of ciclesonide nasal aerosol CIC-hydrofluoroalkane [HFA] with a radiolabeled suspension of mometasone furoate monohydrate aqueous nasal spray MFNS in subjects with either perennial allergic rhinitis AR or seasonal AR.
Initial deposition 2 minutes postdose of radiolabeled CIC-HFA and MFNS in the nasal cavity, nasopharynx, and on nasal wipes, and retention of radioactivity in the nasal cavity and nasal run-out on nasal wipes at 2, 4, 6, 8, and 10 minutes postdose were quantified with scintigraphy.
Full Text Available Anterior nasal spine fractures are a quite rare type of nasal bone fractures. Associated cervical spine injuries are more dangerous than the nasal bone fracture. A case of the anterior nasal spine fracture, in a year-old male was presented. Fracture of the anterior nasal spine, should be considered in the differential diagnosis of the midface injuries and also accompanying cervical spine injury should not be ignored.
Cler, Meredith J. Purpose: This article describes the development and initial validation of an objective measure of nasal air emission NAE using nasal accelerometry.
Method: Nasal acceleration and nasal airflow signals were simultaneously recorded while an expert speech language pathologist modeled NAEs at a variety of severity levels. In addition, microphone and…. Nasal chondromesenchymal hamartoma with no nasal symptoms. The authors present a case of nasal chondromesenchymal hamartoma NCMH in an 8-year-old boy with a 4-month history of frontal headache and no symptoms of nasal obstruction, rhinorrhoea or postnasal drip.
An ENT examination as well as ophthalmology assessment presented normal results. CT scan showed a lesion involving the sphenoid and ethmoid sinuses. The patient had an endoscopic resection of the lesion that was confirmed histologically to be a NCMH. Though NCMH is known to present usually in infants with obstructing nasal mass, an unusual presentation of a patient with throbbing headache without any nasal symptoms is reported here.
Non-European traditional herbal medicines in Europe: a community herbal monograph perspective. Although substantial achievements have been made under the new scheme, only a limited number of herbal medicinal products from non-European traditions commonly used in Europe have been registered.
Therefore, identification of the obstacles, and determination of appropriate means to overcome the major challenges in the registration of non-European traditional herbal medicinal products are of critical importance for the EU herbal medicinal product market.
The primary aims of this study were to understand the key issues and obstacles to registration of non-European traditional herbal medicinal products within the EU. A systematic evaluation of the herbal substances and preparations included in Community herbal monographs and public statements has been carried out.
The focus was herbal substances and preparations derived from non-European traditions. Of the adopted Community herbal monographs, 10 are herbal substances used in Chinese traditional medicine. The most common reasons were the lack of evidence to demonstrate a year minimum.
Relation between epistaxis, external nasal deformity, and septal deviation following nasal trauma. Objectives: To find if the presence of epistaxis after nasal trauma can be used to predict post-traumatic external nasal deformity or a symptomatic deviated nasal septum. Methods: Retrospective analysis of all patients seen in the fractured nose clinic by the first author between 17 October and 27 February Presence of epistaxis, newly developed external nasal deformity, and the presence of a deviated nasal septum with new symptoms of nasal obstruction were noted.
Results: A total of patients were included in the study. Conclusions: Presence of epistaxis after nasal trauma is associated with a statistically significant increase in external nasal deformity. However, one third of patients without epistaxis following nasal trauma also had external nasal deformity and hence all patients with a swollen nose after injury, irrespective of post-trauma epistaxis, still need to be referred to the fractured nose clinic.
Fluid mechanics based classification of the respiratory efficiency of several nasal cavities. The flow in the human nasal cavity is of great importance to understand rhinologic pathologies like impaired respiration or heating capabilities, a diminished sense of taste and smell, and the presence of dry mucous membranes.
The generation of the computational mesh is completely automatic and highly parallelized such that it can be executed efficiently on High Performance Computers HPCs. An evaluation of the functionality of nasal cavities is based on an analysis of pressure drop , secondary flow structures, wall-shear stress distributions, and temperature variations from the nostrils to the pharynx.
The results of the flow fields of three completely different nasal cavities allow their classification into ability groups and support the a priori decision process on surgical interventions. All rights reserved. Characteristics of nasal -associated lymphoid tissue NALT and nasal absorption capacity in chicken. As the main mucosal immune inductive site of nasal cavity, nasal -associated lymphoid tissue NALT plays an important role in both antigen recognition and immune activation after intranasal immunization.
However, the efficiency of intranasal vaccines is commonly restricted by the insufficient intake of antigen by the nasal mucosa, resulting from the nasal mucosal barrier and the nasal mucociliary clearance. The distribution of NALT and the characteristic of nasal cavity have already been described in humans and many laboratory rodents, while data about poultry are scarce. For this purpose, histological sections of the chicken nasal cavities were used to examine the anatomical structure and histological characteristics of nasal cavity.
Besides, the absorptive capacity of chicken nasal mucosa was also studied using the materials with different particle size. Results showed that the NALT of chicken was located on the bottom of nasal septum and both sides of choanal cleft, which mainly consisted of second lymphoid follicle.
A large number of lymphocytes were distributed under the mucosal epithelium of inferior nasal meatus. In addition, there were also diffuse lymphoid tissues located under the epithelium of the concha nasalis media and the walls of nasal cavity.
The results of absorption experiment showed that the chicken nasal mucosa was capable to absorb trypan blue, OVA, and fluorescent latex particles. Inactivated avian influenza virus IAIV could be taken up by chicken nasal mucosa except for the stratified squamous epithelium sites located on the forepart of nasal cavity. The study on NALT and nasal absorptive capacity will be benefit for further understanding of immune mechanisms after nasal vaccination and development of nasal vaccines for poultry.
New CFD tools to evaluate nasal airflow. Computational fluid dynamics CFD is a mathematical tool to analyse airflow. As currently CFD is not a usual tool for rhinologists, a group of engineers in collaboration with experts in Rhinology have developed a very intuitive CFD software.
This is useful complementary information to cover diagnosis, prognosis, or follow-up of nasal pathologies based on quantitative magnitudes linked to airflow. Specialists in Rhinology have been asked for a more intuitive, simple, powerful CFD software to offer more quality and precision in their work to evaluate the nasal airflow. These programs represent a non-invasive, low-cost as the CT scan is already performed in every patient alternative for the functional study of the difficult rhinologic case.
To validate the software, we studied two groups of patients from the Ear Nose Throat clinic, a first group with normal noses and a second group presenting septal deviations. Wall shear stresses are lower in the cases of normal noses in comparison with those for septal deviation.
Besides, velocity field distributions, pressure drop between nasopharynx and the ambient, and flow rates in each nostril were different among the nasal cavities in the two groups. These software modules open up a promising future to simulate the nasal airflow behaviour in virtual surgery intervention scenarios under different pressure or. Nasal mucociliary transport in laryngectomees. A study has been carried out to assess the mucociliary function of nasal mucosa in 30 patients: 16 had undergone surgery due to larynx malignancy and the remaining 14 were divided in two groups.
The first group was composed of seven patients suffering from larynx cancer but not operated, and the second group of seven had pathology not related to the airways control group. The method used a sup 99m technetium sulphur colloid drop deposited on the nasal mucosa of one nostril. To calculate the rate of transport, a new method of quantification has been introduced, based on the formation of a parametric image. The mean velocity in laryngectomees was 3.
It was compared with the group of 14 patients without tracheostomy mean 5. An impaired student's-t-test gave a significant difference between both groups P Herbal Medicine. Herbal medicines are one type of dietary supplement.
They are People use herbal medicines to try to maintain or improve their health. Nasal Wash Treatment. To compare the differences in the clinical therapeutic effects on reflux esophagitis among the combined therapy of huazhuo jiedu jiangni decoction the decoction for resolving the turbid, detoxification and reducing the pathologic upward qi in short and acupuncture, omeprazole and Chinese herbal medicine.
Ninety patients were randomized into 3 groups, 4 cases of them were dropped off. Finally, there were 29 cases in the combined therapy group with acupuncture and the decoction, 29 cases in the western medication group and 28 cases in the Chinese herbal medicine group in the statistical analysis. In the combined therapy group with acupuncture and the decoction, the decoction was prescribed recurrence rate. The therapeutic effects are better than the simple application of either Chinese herbal medicine or omeprazole.
The decoction was applied one dose a day and acupuncture was once a day. In the western medication group, omeprazole capsules, 20 mg were prescribed for oral administration, twice a day. In the Chinese herbal medicine group, the decoction was simply applied. The treatment was 8 weeks in the 3 groups and the follow-up visit was 6 months. The score of reflux disorder questionnaire RDQ and the changes in esophageal mucosa under gastroscope were observed before and after treatment; the clinical therapeutic effects and recurrence rate were evaluated in the 3 groups.
In 4 and 8 weeks of treatment, RDQ scores in the 3 groups were all reduced as compared with those before treatment all P herbal medicine was lower than that in the western medication group P herbal medicine was lower than those in the western medication group and the Chinese herbal medicine group both P herbal medicine group all P Personalized Herbal Medicine?
While drugs remain the cornerstone of medicine, herbal medicine is an important comedication worldwide. Thus, precision medicine ought to face this clinical reality and develop "companion diagnostics" for drugs as well as herbal medicines. This expert review underscores that absent such appropriate attention on both classical drug therapy and herbal medicines, precision medicine biomarkers will likely not stand the full test of clinical practice while patients continue to use both drugs and herbal medicines and, yet the biomarker research and applications focus only or mostly on drug therapy.
We discuss the various dimensions of a future convergence map between herbal and conventional medicine, and conclude with a set of concrete strategies on how best to integrate biomarker research in a realm of both herbal and drug treatment. Africa, by virtue of its vast experience and exposure in herbal medicine and a "pregnant" life sciences innovation ecosystem, could play a game-changing role for the "birth" of biomarker-informed personalized herbal medicine in the near future.
On the relation of nasal cycling with nasal airway dimensions. To determine the extent to which airway areas change in vivo, we used magnetic resonance imaging MRI to quantitate both the cross-sectional area and perimeter of coronal sections of the entire nasal airway of a human subject.
Changes in airway size or patency were indexed to measured changes in unilateral nasal airway resistance determined by posterior rhino manometry.
The results of this study in which two MRI scans were performed for presumed left-side patency and two for right-side patency, showed that changes in nasal airway resistance were difficult to ascribe to systematic changes In the sizes of the airways. Effect of the nasal cycle on congestive response during bilateral nasal allergen provocation. Full Text Available Background. Bilateral nasal allergen provocation usually produces more pronounced obstruction of one nasal passage.
It was found that this could be related to the stage of the nasal cycle before the provocation. To discover whether the stage of the nasal cycle is decisive for asymmetry in congestive response observed during bilateral allergen nasal provocation. Two bilateral nasal allergen provocations were performed in a group of 26 pollen-sensitive volunteers.
Acoustic rhinometry measurements were taken during the nasal cycle, and then after the provocation. A cross-sectional area at the level of the inferior turbinate CSA-2 was measured. Consecutive challenges were performed in the opposite phase of the nasal cycle: the side which had been wide just before the first challenge, was narrow before the second provocation.
Asymmetry in CSA-2 reduction between the nasal passages was observed in most cases. Significant difference was observed between mean CSA-2 reduction rate reactivity of the side that responded with greater congestion, and the opposite side. No significant difference was found in mean CSA-2 reduction rate between the side which was narrow, and the side which was wide before provocation.
Asymmetry of congestive response during bilateral nasal allergen provocation is not dependent on the stage of the nasal cycle preceding the challenge. Recently, the tendency towards complementary therapies such as using herbs with anti-androgenic effects has been increased.
This study reviewed the documents related to the effect of four types of herbal teas on the treatment of PCOS based on the literature review. Results: Among randomized controlled trials RCTs about the effects of herbal medicines on the treatment of PCOS, only four studies were conducted on diverse types of tea.
The results of one study on the effects of mint tea revealed a significant reduction in the total and free testosterone levels in the intervention group P0.
Another clinical trial determined the same effects ofusing Stachys lavandulifolia and hormone therapy. Conclusion: The positive effects of various types of herbal teas on PCOS has been reported in different trials; however, further RCTs are recommended with larger sample size and prolonged duration. Nephrotoxicity and Chinese Herbal Medicine. Chinese herbal medicine has been practiced for the prevention, treatment, and cure of diseases for thousands of years. Herbal medicine involves the use of natural compounds, which have relatively complex active ingredients with varying degrees of side effects.
Some of these herbal medicines are known to cause nephrotoxicity, which can be overlooked by physicians and patients due to the belief that herbal medications are innocuous. Some of the nephrotoxic components from herbs are aristolochic acids and other plant alkaloids.
In addition, anthraquinones, flavonoids, and glycosides from herbs also are known to cause kidney toxicity. The kidney manifestations of nephrotoxicity associated with herbal medicine include acute kidney injury, CKD, nephrolithiasis, rhabdomyolysis, Fanconi syndrome, and urothelial carcinoma. Several factors contribute to the nephrotoxicity of herbal medicines, including the intrinsic toxicity of herbs, incorrect processing or storage, adulteration, contamination by heavy metals, incorrect dosing, and interactions between herbal medicines and medications.
The exact incidence of kidney injury due to nephrotoxic herbal medicine is not known. In addition, exposure to herbal medicine containing aristolochic acid may increase risk for future uroepithelial cancers, and patients require appropriate postexposure screening.
Herbal bathing. Klooster, van 't Charlotte I. Background: Herbal baths play an important role in the traditional health care of Maroons living in the interior of Suriname. However, little is known on the differences in plant ingredients used among and within the Maroon groups. We compared plant use in herbal baths documented for Saramaccan and. Nasal Cancer. Cancer of the nasal cavity and paranasal sinuses is Doctors diagnose nasal cancer with imaging tests, lighted tube-like instruments that Full Text Available BackgroundPathogens in the nasal cavity during nasal surgery could lead to a systemic infectious condition, such as bacteremia, nosocomial infection, or toxic shock syndrome.
However, there is no research about the prevalence of nasal carriage in patients with nasal bone fracture. MethodsThis was a prospective, double-blind, randomized study about the rate of nasal carriage in patients with nasal bone fracture in Korea. Nasal secretions were taken from both the middle nasal meatus and colonized. All analyses were carried out using SPSS software.
ResultsPathogens were identified in of the cases. Coagulase-negative staphylococci CNS were the most cultured bacteria in Staphylococcus aureus was the second most identified pathogen, found in 36 ConclusionsThe prevalence rate of these pathogens in patients with nasal bone fracture in Korea was similar to other reports. However, few studies have addressed the prevalence rate of CNS and MRCNS in accordance with risk factors or the change in prevalence according to specific prophylaxis against infectious complications.
Additional research is needed on the potential connections between clinical factors and microbiological data. Effect of Bilineaster Drop on Neonatal Hyperbilirubinemia. Full Text Available Background: Hyperbilirubinemia is considered one of the most prevalent problems in newborns. Phototherapy, exchange transfusion, and herbal medicine are common therapeutic approaches for preventing any neurologic damage in infants with neonatal jaundice. However, herbal medicine is less commonly used.
Aim: This study aimed to investigate the effect of bilineaster drop on neonatal hyperbilirubinemia. Method: This study was a randomized clinical trial conducted on 98 term neonates aged days with neonatal jaundice admitted to Ghaem Hospital of Mashhad, Iran, during These newborns were randomly assigned into intervention phototherapy and bilineaster drop and control only phototherapy groups.
Total and direct serum bilirubin levels were measured at the time of admission and then 12, 24, 36, and 48 h after treatment. Results: The mean ages of the newborns at the time of admission were 6. Nonetheless, bilirubin levels significantly diminished in both groups over time P. Nasal Glioma: Case report. Full Text Available Nasal gliomas are rare, benign, congenital tumors that are thought to be result of abnormality in embryonic development.
Three types of clinical presentations have been recognized; extranasal, intranasal and combined. Clinically, these masses are non-pulsatile, gray or purple lesions that obstruct the nasal cavity and cause deformity extranasaly.
Histologically, they are made up of astrocytic cells, fibrous and vascular connective tissue that is covered with nasal respiratory mucosa. Treatment of the nasal glioma requires a multidisciplinary approach including an radiologist, neurosurgeon and otorhinolaryngologist. Radiological investigation should be performed to describe intracranial extension.
In this case, a 2 years old boy with nasal mass that was diagnosed as nasal glioma is reported. Immediate effect of benzalkonium chloride in decongestant nasal spray on the human nasal mucosal temperature. Benzalkonium chloride is a preservative commonly used in nasal decongestant sprays.
It has been suggested that benzalkonium chloride may be harmful to the nasal mucosa. Decongestion with the vasoconstrictor xylometazoline containing benzalkonium chloride has been shown to cause a significant reduction of the nasal mucosal temperature.
The purpose of the present study was to determine the short-term influence of xylometazoline nasal spray with and without benzalkonium chloride on the nasal mucosal temperature.
Healthy volunteers 30 were included in the study. Fifteen volunteers received xylometazoline nasal spray 1. Using a miniaturized thermocouple the septal mucosal temperature was continuously measured at defined intranasal detection sites before and after application of the nasal spray.
In both study groups septal mucosal temperatures significantly decreased after decongestion P reduction of the nasal mucosal blood flow following vasoconstriction. This study indicates that benzalkonium chloride itself does not seem to influence nasal blood flow and nasal mucosal temperature in topical nasal decongestants.
Involvement of vascular endothelial growth factor in nasal obstruction in patients with nasal allergy. In the present study we quantitatively analyzed VEGF in the nasal lavage fluid of patients with nasal allergy. We performed nasal antigen challenge with Japanese cedar pollen antigen in 10 healthy adult volunteers and in 10 cedar pollen IgE-positive patients with nasal allergy.
In all patients with nasal allergy, VEGF and histamine levels in the nasal lavage fluid reached a peak 30 min after antigen challenge, then returned to prechallenge values 2 h after antigen challenge. In these patients, the histamine level increased three-fold, while the VEGF level increased fold. However, in all healthy adult volunteers, VEGF and histamine levels did not increase. Nasal Lobular Capillary Hemangioma. Full Text Available Nasal lobular capillary hemangioma is a rare benign tumor of the paranasal sinuses.
This lesion is believed to grow rapidly in size over time. The exact etiopathogenesis is still a dilemma. We discuss a case of nasal lobular capillary hemangioma presenting with a history of epistaxis. Contrast enhanced computed tomography of paranasal sinuses revealed an intensely enhancing soft-tissue mass in the left nasal cavity and left middle and inferior meati with no obvious bony remodeling or destruction.
We present imaging and pathologic features of nasal lobular capillary hemangioma and differentiate it from other entities like nasal angiofibroma. Legal requirements for the quality of herbal substances and herbal preparations for the manufacturing of herbal medicinal products in the European union. In the European Union EU herbal medicinal products have become increasingly important.
This is, for instance, underlined by the recent introduction of a simplified procedure in the Member States of the EU allowing the registration of herbal medicinal products which fulfill the criteria of a traditional herbal medicinal product, i. With regard to the manufacturing of these products and their quality, applications of traditional herbal medicinal products have to fulfil the same requirements as applications for a marketing authorization.
The quality of herbal substances as well as herbal preparations will be determined by the availability of modern science-based public monographs in the European Pharmacopoeia and their equivalents developed by the pharmaceutical industry. The standards put forward in these monographs must allow us not only to define the quality of these products, but also to eliminate dangerous counterfeit, substandard, adulterated and contaminated traditional herbal medicinal products.
The usefulness of these monographs to implement the criteria on quality and specifications put forward for these products in the different guidelines of the European Medicines Agency EMEA is discussed. Marketing herbal medicines. HIV-positive support groups, together with hospital pharmacists in Thailand are fighting the high cost and lack of access to pharmaceuticals by producing and distributing herbal medicines.
In Theung district, Chiang Rai province, members of the local support group for people with HIV produce their own, low-cost, herbal medicines. The herbs are prepared by the group members under the supervision of the pharmacy department at the district hospital. Local people judge their effectiveness by hearing testimonials from people who have witnessed improvement in symptoms.
In response to the popularity and effectiveness of herbal medicines, the Ministry of Public Health has approved plans to sell products derived from local herbs in the pharmacies of government hospitals. Cosmetic reconstruction of a nasal plane and rostral nasal skin defect using a modified nasal rotation flap in a dog. Surgical management of nasal obstruction. The proper evaluation of the patient with nasal obstruction relies on a comprehensive history and physical examination.
Once the site of obstruction is accurately identified, the patient may benefit from a trial of medical management. At times however, the definitive treatment of nasal obstruction relies on surgical management. Recognizing the nasal septum, nasal valve, and turbinates as possible sites of obstruction and addressing them accordingly can dramatically improve a patient's nasal breathing.
Conservative resection of septal cartilage, submucous reduction of the inferior turbinate, and structural grafting of the nasal valve when appropriate will provide the optimal improvement in nasal airflow and allow for the most stable results. Published by Elsevier Inc. The Use of Herbal Medicine in Children. The herbal medicine has been widely used in children for the treatment of several symptoms and the prevention of diseases before accessing the hospital for professionals help.
There are 3 kinds of marketed herbal medicine including empirical based herbal medicine jamu , standardized herbal medicine obat herbal terstandar and clininically tested herbal medicine fitofarmaka. This study aimed to investigate the utilization of the marketed herbal medicine along with non marketed ones which w A guide to herbal remedies. Herbals are not Medicines You have to be careful when using an Editorial team.
Nasal continuous positive airway pressure treatment: current realities and future. Nasal continuous positive airway pressure CPAP is a highly effective treatment for obstructive sleep apnea syndrome.
Subjects slept for a diagnostic night, followed by a treatment night, in the laboratory, using the AutoSet system with full polysomnographic monitoring of respiratory and sleep variables. Arousals were scored using ASDA criteria. Nasalance norms in Greek adults. The purposes of this study were to derive nasalance norms for monolingual Greek speakers, to examine nasalance scores as a function of gender and to draw cross-linguistic comparisons based on normative data.
Participants read aloud a corpus of linguistic material, consisting of 1 a nasal text, an oral text and a balanced text; 2 a set of nasal sentences and four sets of oral sentences and 3 repetitions of each of 12 syllable types 8 oral and 4 nasal. The Nasometer model was used to derive nasalance scores. Mean normative nasalance for spoken Greek was Nasalance scores did not differ significantly with respect to gender. Finally, spoken Greek consistently yielded lower nasalance scores than other languages examined in past work.
The aforementioned normative data on nasalance of young adult speakers of Greek are valid across gender and have direct clinical utility as they provide valuable reference information for the diagnosis and management of Greek adults with resonance disorders caused by velar dysfunction. Perceiving nasal patency through mucosal cooling rather than air temperature or nasal resistance.
Full Text Available Adequate perception of nasal airflow i. The perception of a lack of nasal patency becomes the primary symptom that drives these patients to seek medical treatment. However, clinical assessment of nasal patency remains a challenge because we lack objective measurements that correlate well with what patients perceive. The current study examined factors that may influence perceived patency, including air temperature, humidity, mucosal cooling, nasal resistance, and trigeminal sensitivity.
Forty-four healthy subjects rated nasal patency while sampling air from three facial exposure boxes that were ventilated with untreated room air, cold air, and dry air, respectively.
In all conditions, air temperature and relative humidity inside each box were recorded with sensors connected to a computer. Nasal resistance and minimum airway cross-sectional area MCA were measured using rhinomanometry and acoustic rhinometry, respectively. General trigeminal sensitivity was assessed through lateralization thresholds to butanol.
No significant correlation was found between perceived patency and nasal resistance or MCA. In contrast, air temperature, humidity, and butanol threshold combined significantly contributed to the ratings of patency, with mucosal cooling heat loss being the most heavily weighted predictor. Air humidity significantly influences perceived patency, suggesting that mucosal cooling rather than air temperature alone provides the trigeminal sensation that results in perception of patency.
The dynamic cooling between the airstream and the mucosal wall may be quantified experimentally or computationally and could potentially lead to a new clinical evaluation tool. Surface roughness of composite resin veneer after application of herbal and non- herbal toothpaste.
The aim of this study was to find out the surface roughness of composite resin veneer after brushing. In this study, 24 specimens of composite resin veneer are divided into three subgroups: brushed without toothpaste, brushed with non- herbal toothpaste, and brushed with herbal toothpaste. Brushing was performed for one set of 5, strokes and continued for a second set of 5, strokes. Roughness of composite resin veneer was determined using a Surface Roughness Tester. The results indicate that the highest difference among the Ra values occurred within the subgroup that was brushed with the herbal toothpaste.
In conclusion, the herbal toothpaste produced a rougher surface on composite resin veneer compared to non- herbal toothpaste. Nasal obstruction and sleep-disordered breathing: the effect of supine body position on nasal measurements in snorers. Nasal obstruction is considered to be a potential etiological factor in sleep-disordered breathing.
However, a significant correlation between nasal measurements and obstructive sleep apnea has not been demonstrated so far. The aim of this study was to investigate the relationships between nasal resistance, nasal volumes and selected sleep parameters using nasal measurements performed in both seated and supine positions.
We also investigated whether snoring patients in our clinical sample showed increased positional or decongestive nasal mucosal changes. Forty-one snoring men on a waiting list for correction of nasal obstruction underwent polysomnography, anterior rhinomanometry and acoustic rhinometry. Nineteen non-snoring control subjects were also recruited. Nasal measurements were performed in a seated position, after lying down in a supine position and, after decongestion of nasal mucosa, in a seated position again.
Postural or decongestive changes in nasal measurements were not increased in snoring patients compared with control subjects. The relationship found between nasal measurements and sleep parameters suggests that nasal obstruction does augment airway collapse. Full Text Available Background Pathogens in the nasal cavity during nasal surgery could lead to a systemicinfectious condition, such as bacteremia, nosocomial infection, or toxic shock syndrome. However, there is no research about the prevalence of nasal carriage in patients with nasalbone fracture.
Methods This was a prospective, double-blind, randomized study about the rate of nasalcarriage in patients with nasal bone fracture in Korea. Nasal secretions were taken fromboth the middle nasal meatus and colonized. Results Pathogens were identified in of the cases.
Staphylococcus aureus was the second mostidentified pathogen, found in 36 Conclusions The prevalence rate of these pathogens in patients with nasal bone fracture inKorea was similar to other reports. However, few studies have addressed the prevalence rateof CNS and MRCNS in accordance with risk factors or the change in prevalence according tospecific prophylaxis against infectious complications.
Additional research is needed on thepotential connections between clinical factors and microbiological data. Objective Several types of nasal packs are used postoperatively in septoplasty. In this study, we compared two commonly used nasal packing materials, the intranasal septal splint with airway and Merocel tampon, in terms of pain, bleeding, nasal obstruction, eating difficulties, discomfort in sleep, and pain and bleeding during removal of packing in the early period.
Methods The study group included 60 patients undergoing septoplasty. An intranasal splint with airway was used for the patients in the first group after septoplasty, while Merocel nasal packing was used for the second group. Patients were investigated in terms of seven different factors - pain, bleeding while the tampon was in place, nasal obstruction, eating difficulties, night sleep, pain during removal of the nasal packing, and bleeding after removal of packing.
Nasal septal hematoma. A nasal septal hematoma is a collection of blood within the septum Multiple chromatographic fingerprinting and its application to the quality control of herbal medicines. Recently, chromatographic fingerprinting has become one of the most powerful approaches to quality control of herbal medicines. However, the performance of reported chromatographic fingerprinting constructed by single chromatogram sometimes turns out to be inadequate for complex herbal medicines, such as multi-herb botanical drug products.
In this study, multiple chromatographic fingerprinting, which consists of more than one chromatographic fingerprint and represents the whole characteristics of chemical constitutions of the complex medicine, is proposed as a potential strategy in this complicated case. Moreover, the authentication and validation of the binary fingerprints were performed. Then, a data-level information fusion method was employed to capture the chemical information encoded in two chromatographic fingerprints.
Based on the fusion results, the lot-to-lot consistency and frauds can be determined either using similarity measure or by chemometrics approach. The application of binary chromatographic fingerprinting to consistency assessment and frauds detection of DSDP clearly demonstrated that the proposed method was a powerful approach to quality control of complex herbal medicines.
Nasal capillariasis in a dog. A five-year-old dog was evaluated for chronic nasal discharge. Nasal infection caused by Capillaria aerophila was diagnosed by identification of adult nematodes and eggs in the nasal flush sediment and by nasal biopsy samples and eggs in faecal flotations.
Reinfection occurred following treatment with fenbendazole and ivermectin, probably because of a contaminated housing area. Measurement with nasal scintigraphy of nasal mucociliary clearance in normal man. Nasal mucociliary function was evaluated by nasal scintigraphy in normal subjects. A microdrop of HSA or saline labelled with 99m Tc was dripped into the middle part of each middle meatus in the nasal cavity and its clearance was observed by scinticamera. The accumulated concentration of RI was determined every 30 seconds for 10 minutes.
Nasal resistance was measured by rhinomanometry with the oscillation method. In nonsmokers, there is a significant negative correlation between nasal resistance and clearance rate, suggesting that the more patent the nose, the faster the mucociliary clearance.
When both nostrils were closed, the clearance rate was significantly depressed. When one nostril was closed, there was no significant effect on clearance. Nasal resistance was decreased by exercise with a bicycle ergometer.
Nasal mucociliary clearance was slightly decreased after exercise but not significantly so. Image diagnosis of nasal bone fracture. Twenty cases of nasal bone fractures were evaluated as to the types of fractures based upon HRCT findings. Nasal bone fractures were classified into lateral and frontal fractures.
HRCT images were evaluated in three planes including upper, middle and lower portions of the nasal bone. Fractures favored males of teens. Lateral fracture gave rise to the fractures of the nasal bone opposite to the external force, loosening of the ipsilateral nasomaxillary sutures and fractures of the frontal process of the maxilla.
Conventional X-Ray films were reevaluated after HRCT evaluation and indications of nasal bone fractures were determined. In addition to the discontinuity of the nasal dorsum, fracture lines parallel to and beneath the nasal dorsum and indistinct fracture lines along the nasomaxillary sutures are the indication of nasal bone fractures by conventional X-Ray films.
Full Text Available Herbs are environmentally friendly commodities that slogan 'back to nature'. Herbal is a reliable commodityIndonesia because herbal raw material comes from Indonesia's abundant biodiversity. However, the currentIndonesian herbal faced a number of challenges to be able to compete with the herbs that come from foreigncountries. The existence of the Free Trade Agreement can be seen by the opening of the market to the entry ofIndonesian herbal products imported from Cina, India, Malaysia, and others.
Economically, Indonesia's tradebalance deficit with export figures of herbal products continues to decline. That is, the existence of free tradeagreements is adversely affected by the low competitiveness of herbal products against imported products thatcirculate in Indonesia. Will EAC able to lift Indonesian herbal products from the domestic market?. Full Text Available Use of herbal medicine in the treatment of liver cancer has a long tradition.
The compounds derived from the herb and herbal composites are of considerable interest among oncologists.
In the past, certain herbal compounds and herbal composite formulas have been studied through in vitro and in vivo as an anti-hepatocellular carcinoma HCC agent, enhancing our knowledge about their biologic functions and targets.
However there is a significant distinction between the herbal medicine and the herbal production even though both are the plant-based remedies used in the practice. In this article, for the sake of clarity, the effective herbal compounds and herbal composite formulas against HCC are discussed, with emphasizing the basic conceptions of herbal medicine in order to have a better understanding of the prevention and treatment of HCC by herbal active compounds and herbal composite formulas.
Conclusions: Local nasal immunotherapy may be clinically useful for allergic nasal blockage associated with nasal hyperresponsiveness. The mechanisms responsible for this effectiveness might not be related to IgE production.
Additionally, the effectiveness for nasal tissue was dissociated from that seen for the ocular tissue. Prescription for herbal healing. John's Wort, to less familiar remedies, such as khella and prickly ash Chinese and ayurvedic herbal combinations Discussion of more than common disorders from acne to yeast infection, and suggested herbal treatment therapies" Full Text Available Nasal polyps are inflammatory proliferative tumors arising from the mucosa of the nasal cavity and paranasal sinuses.
Although many cases concerning nasal polyps have been reported, those involving external nasal deformities are rare. We report a case of nasal polyposis filling the nasal cavity and paranasal sinuses, leading to external nasal and facial deformities. An evaluation of selected herbal reference texts and comparison to published reports of adverse herbal events.
There has been a recent proliferation of medical reference texts intended to guide practitioners whose patients use herbal therapies. We systematically assessed six herbal reference texts to evaluate the information they contain on herbal toxicity.
We selected six major herbal references published from to to evaluate the adequacy of their toxicological information in light of published adverse events. We searched Medline to to identify published reports of adverse effects potentially related to these same 12 herbs. We scored each herbal reference text on the basis of information inclusiveness for the target 12 herbs, with a maximal overall score of 3. The herbs, identified on the basis of CPCS-SF call frequency were: St John's wort, ma huang, echinacea, guarana, ginkgo, ginseng, valerian, tea tree oil, goldenseal, arnica, yohimbe and kava kava.
The overall herbal reference scores ranged from 2. The Natural Medicines Comprehensive Database received the highest overall score and was the most complete and useful reference source. All of the references, however, lacked sufficient information on management of herbal medicine overdose, and several had incorrect overdose management guidelines that could negatively impact patient care. Current herbal reference texts do not contain sufficient information for the assessment and management of adverse health effects of botanical therapies.
To build a well-off society in an all-round way, eliminate poverty, improve people's livelihood and improve the level of social and economic development in poverty-stricken areas is the frontier issues of the government and science and technology workers at all levels. Chinese herbal medicine is the strategic resource of the people's livelihood, Chinese herbal medicine cultivation is an important part of China's rural poor population income. As most of the production of Chinese herbal medicine by the biological characteristics of their own and the interaction of natural ecological environment factors, showing a strong regional character.
There is already a good base of Chinese herbal medicine industry, which is the key priority area for poverty alleviation of Chinese herbal medicine industry. Herbal Medicine - Multiple Languages. Cosmetic and Functional Nasal Deformities. A cosmetic or functional nasal deformity may occur secondary to Smart Polymers in Nasal Drug Delivery.
Nasal drug delivery has now been recognized as a promising route for drug delivery due to its capability of transporting a drug to systemic circulation and central nervous system. Though nasal mucosa offers improved bioavailability and quick onset of action of the drug, main disadvantage associated with nasal drug delivery is mucocilliary clearance due to which drug particles get cleared from the nose before complete absorption through nasal mucosa.
Therefore, mucoadhesive polymeric approach can be successfully used to enhance the retention of the drug on nasal mucosal surface.
Here, some of the aspects of the stimuli responsive polymers have been discussed which possess liquid state at the room temperature and in response to nasal temperature, pH and ions present in mucous, can undergo in situ gelation in nasal cavity. In this review, several temperature responsive, pH responsive and ion responsive polymers used in nasal delivery, their gelling mechanisms have been discussed.
Smart polymers not only able to enhance the retention of the drug in nasal cavity but also provide controlled release, ease of administration, enhanced permeation of the drug and protection of the drug from mucosal enzymes. Thus smart polymeric approach can be effectively used for nasal delivery of peptide drugs, central nervous system dugs and hormones.
With the development of society and the improvement of people's living standards, the effect of Chinese medicine in treatment and health care is more and more prominent. The herbal decoction pieces are the important part of Chinese medicine,it can be applied directly to clinical treatment and it's also the raw material of Chinese patent medicine. We delight in ensuring that your event is one to remember, surpassing all of your expectations. Your creativity is the only limit to what you can do.
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